See what causes headaches to help avoid them. Where to Buy. For adults and children 12 years of age and older. Uses temporarily relieves minor aches and pains due to: the common cold headache backache minor pain of arthritis toothache muscular aches premenstrual and menstrual cramps temporarily reduces fever. Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4, mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: acetaminophen may cause severe skin reactions.
Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen prescription or nonprescription. If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.
Directions do not take more than directed see overdose warning adults and children 12 years and over take 2 tablets every 6 hours while symptoms last do not take more than 6 tablets in 24 hours, unless directed by a doctor do not use for more than 10 days unless directed by a doctor children under 12 years ask a doctor.
Don't Have an Account? Sign Up Now! Use another account. Sign In. You are Now Registered! Acetaminophen is a pain reliever for mild to moderate pain, such as headaches, muscles aches, backache, and toothaches, and fevers.
Oral tablets, extended-release tablets: 30 to 45 minutes. Intravenous acetaminophen: 5 to 10 minutes. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. It is only recommended that you split pills in half, not any smaller.
Select basic ads. Create a personalised ads profile. Select personalised ads. Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. In Chicago in the fall of , Tylenol acetaminophen capsules were found to be laced with cyanide, which proved quickly fatal in seven unwitting victims.
To this day, law enforcement has yet to catch the person or people responsible for this heinous act. In what is now routinely used as a crisis management case study, at the height of the Tylenol panic, McNeil Consumer Products issued mass public warnings and recalled all existing Tylenol bottles, 31 million in total. McNeil Consumer Products also assured the public that all tampering occurred outside the factory.
During the crisis and over the years since, in the hearts and minds of the public, Tylenol has engendered enduring good faith as a safe, affordable, and effective pain reliever. However, for reasons besides the now remote threat of criminal tampering, Tylenol can be dangerous. Few people probably consider that when taken in excess, acetaminophen can cause fatal liver failure.
After all, bottles of acetaminophen look innocuous on medicine cabinet or store shelves. Fortunately, the repercussions of acetaminophen poisoning can be averted if an antidote is administered within the first eight hours of poisoning.
In the body, Tylenol enters circulation through the gastrointestinal tract. When taken correctly, it can be effective.
However, Tylenol overdose is one of the most common poisonings, and it can be deadly if taken in large doses. It takes about 30 minutes for the analgesic pain-relieving and antipyretic fever-breaking properties of this medication to take effect, and, under normal circumstances, our bodies clear about half a dose of Tylenol 2.
When taken for pain in adults, Tylenol is dosed between milligrams and 1, milligrams every four to six hours. Current guidelines note the maximum daily dose is 3 grams equal to 3, milligrams of Tylenol a day.
Some Tylenol caplets contain as much as milligrams of acetaminophen, so you should never take more than two caplets every six hours or four caplets per day. Consult with your physician if you have a painful condition that requires you to take four caplets of Tylenol a day. When taken in therapeutic amounts, most Tylenol is safely broken down by the liver through the metabolic processes of sulfation and glucuronidation.
Finally, with therapeutic dosages, a very small percentage is oxidized by the cytochrome P system reactive metabolite N-acetyl- p -benzoquinoneimine NAPQI ; NAPQ1 is quickly detoxified by hepatic glutathione to a nontoxic acetaminophen-mercapturate compound, which is also eliminated by the kidneys. In cases of Tylenol poisoning, the liver enzyme cytochrome P is quickly overwhelmed, and stores of glutathione run out.
Consequently, the reactive metabolite, NAPQ1, damages and kills liver cells, thus leading to liver failure.
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